论文部分内容阅读
目的探讨Ⅰ、Ⅱ类群体反应性抗体、MICA抗体对肾移植恢复的影响。方法本实验室应用免疫磁珠法检测术前、术后1、2、4周肾移植患者体内群体反应性抗体及MICA抗体,共检测700人次。结果术前男性抗体阳性率24%(63/262),女性抗体阳性率40%(46/116),术后延迟恢复组与急性排斥组的群体反应性抗体Ⅰ、Ⅱ类、MICA抗体均高于正常恢复组。结论群体反应性抗体I、Ⅱ类及MICA抗体与移植恢复关系密切,术前抗体筛选及术后抗体检测对肾移植意义重大。
Objective To investigate the effect of MICA antibodies on the recovery of renal transplant recipients of group Ⅰ and group Ⅱ. Methods In our laboratory, immunoreactive beads and MICA antibodies were detected in preoperative and postoperative 1, 2 and 4 weeks after transplantation in renal transplant recipients. A total of 700 tests were performed. Results The positive rate of preoperative male antibody was 24% (63/262) and the positive rate of female antibody was 40% (46/116). The levels of reactive antigens I, II and MICA in postoperative delayed recovery group and acute rejection group were higher In the normal recovery group. Conclusions Group I, II and MICA antibodies are closely related to transplantation recovery. Preoperative antibody screening and postoperative antibody testing are of great significance to renal transplantation.