目的观察莪术油经动脉灌注对大鼠移植性肝癌的治疗作用．方法复制４０只大鼠移植性肝癌模型，随机分为治疗组与对照组，每组各２０只．经胃十二指肠动脉至肝固有动脉分别灌注莪术油（１０ｍｇ／ｋｇ）及生理盐水（０２ｍＬ～０３ｍＬ）．结果与对照组比较，莪术油治疗组大鼠的肿瘤生长（ＧＲ）受到显著抑制（１０８％±４５％ｖｓ２０６％±１２７％，Ｐ＜００５），肿瘤坏死程度加重（Ｐ＜００１），生存时间明显延长（１４８ｄ±３４ｄｖｓ１１７ｄ±１９ｄ，Ｐ＜００５）．结论莪术油经肝动脉灌注对大鼠移植性肝癌具有治疗作用． 5. Objective To observe the therapeutic effect of Rhizoma Curcumae Curing with arterial perfusion on transplanted liver cancer in rats. Methods Forty rats with transplanted hepatocellular carcinoma were randomly divided into treatment group and control group, with 20 rats in each group. The gastroduodenal artery to the hepatic artery were infused with erysipelas oil (10 mg/kg) and physiological saline (0.2 mL to 0.3 mL). Results Compared with the control group, the tumor growth (GR) was significantly inhibited in the zedoary oil treatment group (108%±45% vs206%±127%, P<005), tumor necrosis. The degree of aggravation (P<001) was significantly prolonged (148d±34dvs117d±19d, P<005). 4. Conclusions Curcuma oil has hepatic arterial perfusion to treat transplanted liver cancer in rats.