自1974年6月起,我们应用液氮低温治疗口腔粘膜白斑近100余例。1976年、1978年作者曾先后在“新医学”、“人民军医”杂志上作过报告,对材料、方法、疗效、合并症及注意事项进行了介绍,本文拟报告液氮冷冻口腔白斑4～6年患者随访结果,以了解冷冻对口腔白斑的治疗价值,现报告如下: Since June 1974, we have used liquid nitrogen cryotherapy to treat about 100 cases of oral leukoplakia. In 1976 and 1978, the author had made reports in the “New Medicine” and “People’s Military Medical” magazines. He introduced the materials, methods, efficacy, complications, and precautions. This article is intended to report liquid nitrogen frozen oral leukoplakia. 6-year patient follow-up results to understand the value of cryotherapy for oral leukoplakia are reported as follows: