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50年代到60年代,以色列军队临床传染性肝炎的年发病率为4~14‰,居民中为0.7~0.9‰.不同部队每3~4年发生大的流行,流行期间年发病率可达10~14‰.1977年~1983年间的调查发现以军传染性肝炎中84%为甲型肝炎,5%为乙型肝炎,11%为非甲非乙型肝炎.1970年实施用免疫血清球蛋白(ISG)作暴露后预防的方针,即在发现病例后对整个部队用2ml ISG肌注作免疫预防,年发病例从10~14‰降到1970~1977年
Between the 1950s and the 1960s, the annual incidence of clinical infectious hepatitis in the Israeli army was 4-14 ‰, and among residents was 0.7-0.9 ‰. Large outbreaks occurred every 3 to 4 years among different units and the annual incidence rate during the epidemic could reach 10 ~ 14 ‰ .The survey from 1977 to 1983 found that 84% of Israeli infectious hepatitis was hepatitis A, 5% were hepatitis B, and 11% were non-A, non-hepatitis B. In 1970, immunoglobulin (ISG) as a strategy for post-exposure prophylaxis, ie immunization of the entire force with 2 ml of ISG intramuscularly after the case was found, with annual incidence falling from 10-14% to 1970-1977