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目的对132例确诊埃可病毒脑炎患儿的脑脊液和脑电图改变进行分析。方法分析患儿临床体征,行脑脊液白细胞、蛋白定性、糖、氯化物检验及细菌培养,行脑电图检查。结果所有患儿均有发热、头痛症状,多有呕吐(94.7%),头晕、烦躁不安和腹泻较少;脑脊液白细胞总数均增高,63.6%为(100～499)×106/L,(10～99)×106/L和(500～999)×106/L各占17.4%,以淋巴细胞为主;有87例(65.9%)脑电图显示异常,其中轻度异常占34.5%,中度48.3%,重度17.2%。结论对临床疑似埃可病毒脑炎患儿,如果脑电图正常,应尽早做脑脊液检查,进行综合诊断,以免延误治疗。
Objective To analyze the changes of CSF and EEG in 132 children with confirmed echovirus encephalitis. Methods The clinical signs of children were analyzed. Cerebrospinal fluid leukocytes, protein qualitative analysis, sugar and chloride test and bacterial culture were performed. EEG examination was performed. Results All patients had fever, headache symptoms, vomiting (94.7%), dizziness, restlessness and diarrhea. The total number of cerebrospinal fluid leukocytes increased with 63.6% (100-499) × 106 / L, 99) × 106 / L and (500 ~ 999) × 106 / L each accounted for 17.4%, mainly lymphocytes; 87 (65.9%) EEG showed abnormal, of which mild dysfunction accounted for 34.5%, moderate 48.3%, severe 17.2%. Conclusion In children with suspected echovirus encephalitis, if the EEG is normal, cerebrospinal fluid examination should be done as soon as possible to make a comprehensive diagnosis so as to avoid delay treatment.