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目的对郴州市2006-2009年流行性感冒流行病学和病原学监测结果进行分析。方法采集流感样病例(ILI)的鼻、咽拭子标本用狗肾细胞(MDCK)进行病毒分离培养,采用血凝(HA)及血凝抑制(HI)方法进行病毒初筛及分型鉴定。结果 2006-2009年4所哨点医院共报告ILI 21 960例,平均ILI就诊百分比为2.30%,共检测ILI鼻、咽拭子标本5 350份,分离到季节性流感阳性毒株607株,阳性率11.35%,主要流行毒株为A(H1N1)和A(H3N2),在不同年份交替流行,其次每年都有B型流感病毒存在。疑似流感疫情标本1 228份,阳性毒株779份,阳性率63.44%,2006-2008年郴州市流感暴发疫情以B型为主,2009年郴州市流感暴发疫情以甲型H1N1型为主,季节性流感病毒也较活跃。结论 2006-2009年郴州市流行的流感毒株主要有季节性H1N1亚型、H3N2亚型、B型流感病毒和甲型H1N1流感病毒4种,流感流行有明显的季节性,暴发疫情主要发生在学校。
Objective To analyze epidemiological and epidemiological surveillance results of influenza in Chenzhou from 2006 to 2009. Methods Nasopharyngeal and throat swab samples of influenza-like illness (ILI) were collected and isolated from dog’s kidney cells (MDCK). Hemagglutination (HA) and hemagglutination inhibition (HI) Results A total of 960 cases of ILI were reported in 4 sentinel hospitals between 2006 and 2009, with an average ILI rate of 2.30%. A total of 5350 samples of ILI nasal and throat swabs were detected, and 607 strains of seasonal influenza were isolated. Positive Rate of 11.35%, the main epidemic strains A (H1N1) and A (H3N2), alternating in different years, followed by influenza B virus every year. Suspected influenza samples 1 228, 779 positive strains, the positive rate of 63.44%, 2006-2008 outbreaks of influenza outbreak in Chenzhou City to B-type, 2009, outbreaks of flu in Chenzhou City to H1N1-based, season Sexually transmitted viruses are also more active. Conclusions There are four seasonal influenza H1N1, H3N2, B and H1N1 influenza strains in Chenzhou City during 2006-2009. Influenza pandemic was seasonal. The outbreak mainly occurred in SCHOOL.