先兆子痛即重度妊娠高血压综合症，是孕产妇死亡的重要原因之一，近年来，国外很多学者认为妊高症与血管活性物质调节失常有关。研究表明，血管紧张素D水平的升高能导致蜕膜组织中螺旋动脉的纤维样坏死，因此血管紧张素原（an－giMmp，ACF）基因与先兆子痛的关系日益引起人们的 Preeclampsia is severe pregnancy-induced hypertension syndrome, which is one of the important causes of maternal death. In recent years, many foreign scholars think that pregnancy-induced hypertension is associated with dysregulation of vasoactive substances. Studies have shown that elevated angiotensin D levels can lead to fibrotic necrosis of the spiral arteries in the decidua. Therefore, the relationship between the angiotensinogen (angiotensinogen) gene and preeclampsia is increasingly aroused