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黄酮木素酚或黄醇木素酚是很重要的天然多酚类物质,因其有保肝作用,可用以治疗肝硬变。但这类化合物实际并不是真正的木酚素,而只是类黄酮与松柏醇相缩合的产物。现从花旗松(Pseudotsuga menziesii(Mirb) Franco)的树皮外层中分离到一个真正的黄酮木脂素(Ⅰ),其结构中有一个二氢五羟黄酮,通过一个联苯链与松脂酚相接,暂命名为花旗松醇(pseudotsuganol),其结构式如(Ⅰ)。本品系用醋酸乙酯从花旗松树皮外层提取,在交联葡聚糖凝胶LH-20上用乙醇进行初步再分离后,用MCI凝胶-CHP-20P柱上进行反相分离(用3:7v/v的甲醇:水洗
Flavone lignin or xanthophyll phenol is a very important natural polyphenols. Because of its liver protection, it can be used to treat liver cirrhosis. However, these compounds are not actually lignans but rather are the products of condensation of flavonoids with coniferyl alcohol. A real flavonolignant (I) has been isolated from the outer bark of Douglas-fir (Pseudotsuga menziesii (Mirb) Franco) and has a dihydroquercetin structure in its structure, through a biphenyl chain and rosinol. Connected, tentatively named as sputum tsuganol, its structural formula as (I). This product was extracted from the outer layer of Douglas fir bark with ethyl acetate, and then separated on ethanol by a Sephadex LH-20, and then separated by reversed phase separation on an MCI gel-CHP-20P column ( With 3:7 v/v methanol: water wash