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目的观察不稳定性心绞痛患者窦性心率震荡现象(HRT),研究其临床变化的意义。方法选择不稳定性心绞痛(UA)患者及心肌梗死患者各100例,根据24h动态心电图数据,计算窦性心率震荡参数,即震荡初始(TO)及震荡料率(TS),比较两组T0及TS的差别,分析TO及TS与左室射血分数、左室舒张末容2积及心率变异性指标(SDNN和SDANN)的相关性,并观察治疗半年后实验组相关窦性心律震荡指标的变化情况。结果实验组TO、TS、SDNN及左室射血分数显著低于对照组,且其SDANN以及LVEDD,显著高于对照组。两组对比,差异具有统计学意义(P<0.05)。实验组TO、TS与SDNN、SDANN、左室射血分数和左室舒张末容积具有显著的相关性,且其治疗半年后的TO、TS、SDNN、SDANN、LVEF以及LVEDD,均显著优于治疗前。治疗前后比较,差异显著,有统计学意义(P<0.05)。结论 UA患者窦性心率震荡减弱,且经冠心病二级预防后,可明显改善UA患者的窦性心率震荡。
Objective To observe the sinus rhythm of heart rate (HRT) in patients with unstable angina and to study its clinical significance. Methods 100 patients with unstable angina pectoris (UA) and patients with myocardial infarction were enrolled in this study. Sinusoidal vibration parameters (TO and TS) were calculated according to 24h Holter data. T0 and TS , The correlation between TO and TS, left ventricular ejection fraction, left ventricular end-diastolic volume, and heart rate variability (SDNN and SDANN) were analyzed. The change of sinus rhythm related indicators in experimental group after 6 months of treatment Happening. Results The TO, TS, SDNN and left ventricular ejection fraction in the experimental group were significantly lower than those in the control group, and their SDANN and LVEDD were significantly higher than those in the control group. The difference between the two groups was statistically significant (P <0.05). There were significant correlations between TO, TS, SDNN, SDANN, left ventricular ejection fraction and left ventricular end-diastolic volume in the experimental group, and TO, TS, SDNN, SDANN, LVEF and LVEDD after six months before. Before and after treatment, the difference was significant, with statistical significance (P <0.05). Conclusions The sinus rhythm of UA patients is weakened, and after secondary prevention of coronary heart disease, sinus rhythm of UA patients can be obviously improved.