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[目的]探讨弥散加权成像(DWI)在肝细胞肝癌和胆管细胞癌鉴别诊断中的价值。[方法]19例经病理证实的肝细胞肝癌患者和10例经病理证实的胆管细胞癌患者进行MR检查,DWI采用单次激发平面回波成像序列,在工作站上进行ADC值测量。[结果]肝细胞肝癌和胆管细胞癌的ADC值分别为1.162×10-3±0.045×10-3mm2/s和1.484×10-3±0.191×10-3mm2/s,均低于正常肝脏组织的1.780×10-3±0.492×10-3mm2/s。肝细胞肝癌和胆管细胞癌的ADC值有统计学差异(P<0.01),两者的瘤/肝值也有统计学差异。[结论]依据磁共振弥散成像的DWI图像、ADC值,对肝细胞肝癌和胆管细胞癌的鉴别诊断有一定价值。
[Objective] To investigate the value of diffusion-weighted imaging (DWI) in the differential diagnosis of hepatocellular carcinoma and cholangiocarcinoma. [Methods] Twenty-nine patients with pathologically confirmed hepatocellular carcinoma and 10 patients with pathologically confirmed cholangiocarcinoma were examined by MR imaging. DWI was performed on a workstation using a single excitation plane echo imaging sequence to measure ADC values. [Results] The ADC values of hepatocellular carcinoma and cholangiocarcinoma were 1.162 × 10-3 ± 0.045 × 10-3mm2 / s and 1.484 × 10-3 ± 0.191 × 10-3mm2 / s respectively, both lower than that of normal liver tissue 1.780 × 10 -3 ± 0.492 × 10 -3 mm 2 / s. The ADC values of hepatocellular carcinoma and cholangiocarcinoma were statistically different (P <0.01), and the tumor / liver values of the two groups were also significantly different. [Conclusion] DWI images and ADC values based on MR diffusion imaging have certain value in the differential diagnosis of hepatocellular carcinoma and cholangiocarcinoma.