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目的探讨超声造影在子宫平滑肌瘤诊断中的应用价值。方法采用造影剂SonoVue联合造影匹配成像技术对23例子宫平滑肌瘤患者进行实时超声造影检查。观察病灶内造影剂灌注过程及造影后声像图特征,分析时间强度曲线。结果 23例子宫平滑肌瘤共37个病灶均可见不同程度强化,根据病灶增强模式可分为3类:高增强(75.7%)等增强(16.2%)及低增强(8.1%)。分析时间强度曲线,子宫平滑肌瘤造影剂消退快于正常子宫肌层(t=5.69,P=0.00)。结论子宫平滑肌瘤超声造影增强模式具有一定的特征,其与周围正常肌层在增强时间与强度上的差异,有助于显示病灶及其与周围组织的关系。
Objective To investigate the value of contrast-enhanced ultrasound in the diagnosis of uterine leiomyomas. Methods 23 cases of uterine leiomyoma were examined by real-time contrast-enhanced ultrasound with SonoVue contrast-imaging technique. The contrast agent perfusion process and post-contrast sonography features were observed and the time intensity curve was analyzed. Results Totally 37 lesions of 23 cases of uterine leiomyoma were observed with different degrees of enhancement. According to the mode of lesion enhancement, they could be divided into three groups: high enhancement (75.7%) and low enhancement (16.2%). Analysis of time intensity curves, uterine leiomyoma contrast agent subsides faster than the normal myometrium (t = 5.69, P = 0.00). Conclusions The mode of enhancement of uterine leiomyoma with contrast-enhanced ultrasound has some characteristics, which is different from the surrounding normal muscular layer in enhancing time and intensity, which helps to show the relationship between lesion and its surrounding tissues.