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本文报道了细粒棘球绦虫原头节在NIH小鼠体内发育过程的组织化学变化,结果如下: 一、糖原:感染后1～2周,原头节体内糖原含量明显减少或消失;4周～6个月,生发层内出现糖原并陆续增加。 二、核酸及蛋白质:感染后1～4周,原头节体内的核酸及蛋白质含量均有逐渐减少的趋势;2～3个月时,生发细胞内的上述生化物质含量仍然较少;感染后4～6个月,凡在芽状增殖的生发层内,其聚集生发细胞中均含有相当丰富的核酸及蛋白质成分。 三、AKP、ATP及ACP酶感染后1～2周,原头节体内AKP及ATP酶的活力逐渐减弱;但在4周～6个月,生发层内的酶活力有所增强;原头节皮层内的ACP活力则在感染后1～2周才开始显现;但4周后活力减弱,感染后2～6个月,生发层内ACP的活力又逐渐增强。 对细粒棘球绦虫不同时期幼虫的上述生化物质动态变化的生理意义,进行了扼要的讨论。
In this paper, we report the histochemical changes of the protoscoleces of Echinococcus granulosus in NIH mice. The results are as follows: 1. Glycogen: The content of glycogen in the protoscoleces decreased or disappeared 1 ~ 2 weeks after infection. 4 weeks ~ 6 months, the germinal layer appears glycogen and gradually increased. Nucleic acid and protein: 1 to 4 weeks after infection, the content of nucleic acid and protein in the original headdressing tended to decrease gradually. After 2 ~ 3 months, the above biochemical contents in germinal cells were still low; after infection 4 to 6 months, where germinal proliferation in the germinal layer, the aggregated germinal cells contain a very rich nucleic acid and protein components. AKP, ATP and ACP enzyme 1 to 2 weeks after infection, AKP and ATP enzyme activity of the original head section gradually weakened; but in 4 weeks ~ 6 months, the germinal layer within the enzyme activity increased; the original head section ACP activity in the cortex began to manifest 1-2 weeks after infection, but after 4 weeks the activity was weakened. After 2 to 6 months after infection, the activity of ACP in the germinal layer was gradually increased. The physiological significance of the above biochemical changes in the echinococcus granulosus at different stages was briefly discussed.