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目的探讨嗜麦芽窄食单胞菌呼吸机相关性肺炎(VAP)的临床特征。方法对48例嗜麦芽窄食单胞菌VAP的临床资料进行回顾性分析。结果 48例嗜麦芽窄食单胞菌对氧氟沙星、米诺环素、复方新诺明的敏感率分别为48.1%、41.2%、36.5%,晚发VAP发生率79.17%,病死率60.4%,31例有使用碳青霉烯类抗生素病史,临床表现为感染中毒症状重,不规则发热,黄色黏痰,肺部湿啰音,胸片常有下肺阴影或胸腔积液。结论嗜麦芽窄食单胞菌VAP在院内感染中占有重要地位,应进行针对性预防及治疗。
Objective To investigate the clinical characteristics of Stenotrophomonas maltophilia ventilator-associated pneumonia (VAP). Methods The clinical data of 48 cases of Stenotrophomonas maltophilia VAP were retrospectively analyzed. Results The susceptibility of 48 STIs, minocycline and cotrimoxazole were 48.1%, 41.2% and 36.5% in 48 cases of Stenotrophomonas maltophilia, respectively. The incidence of VAP in late onset was 79.17% and the mortality was 60.4 %, 31 cases had a history of using carbapenem antibiotics, clinical manifestations of severe symptoms of poisoning, irregular fever, yellow phlegm, pulmonary wet rales, chest x-ray often have lower shadow or pleural effusion. Conclusion Stenotrophomonas maltophilia VAP plays an important role in the nosocomial infection and should be targeted prevention and treatment.