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目的 观察MA方案治疗老年难治性急性非淋巴细胞白血病的临床疗效和毒副作用。方法 采用米托嗯醌(mitoxantrone)和阿糖胞苷(cytarabine)联合化疗。结果 10例患者中4例取得完全缓解,1例取得部分缓解,缓解率达50％。结论 在强力支持治疗的基础上,MA方案治疗老年难治性急性非淋巴细胞白血病有较好的疗效,其毒副作用可以耐受。
Objective To observe the clinical efficacy and side effects of MA regimen in the treatment of elderly refractory acute non-lymphocytic leukemia. Methods Mitoxantrone and cytarabine combined with chemotherapy. Results Among 10 patients, 4 patients achieved complete remission, 1 achieved partial remission, and the remission rate reached 50%. Conclusion On the basis of strong supportive treatment, MA regimen has a good curative effect in the treatment of senile refractory acute non-lymphocytic leukemia and the toxic side effects can be tolerated.