论文部分内容阅读
癌变的早期诊断对提高疗效具有特殊意义。为了寻求简捷、高效、超前、可靠的诊断方法，实验以DMBA（二甲基苯并直）诱导的金地鼠颊囊致癌模型为对象，以PCNA（增殖细胞核抗原）、BrdV（澳脱氧尿嘧啶）等免疫组化技术为手段，以光镜观察诊断为对照，对三种观察结果进行相关分析，发现三者间有高度显著的相关性，证实了免疫组化方法在癌变诊断中有一定的参考价值。实验还发现PCNA和BrdU检测结果比较敏感、简捷，可靠性较好，因而是很有希望的早期诊断癌变的手段之一。
Early diagnosis of cancer has the special meaning of improving the curative effect. In order to find a simple, efficient, advanced and reliable diagnostic method, the experiment used DMBA (dimethylbenzothiazide) -induced hamster cheek pouch carcinogenicity model as PCNA (proliferating cell nuclear antigen), BrdV And other immunohistochemical techniques as a means to observe the diagnosis by light microscopy as a control, the correlation analysis of the three observations found that there was a highly significant correlation between the three confirmed that immunohistochemistry in the diagnosis of cancerous have some reference value. The experiment also found that PCNA and BrdU test results are more sensitive, simple, better reliability, and therefore is one of the promising early detection of cancer.