论文部分内容阅读
作者们详尽地报道了Darenthin的药理作用及其临床试用的初步结果。 Darenthin(P-甲苯磺酸N-O-溴苯甲基- N-乙基:N:N-=甲铵)是一种新作用类型的降血压药,它选择地阻断周围交感神经(肾上腺素能神经)系统,但没有拮颃肾上腺素或正肾上腺素的作用,而且这种阻断作用不併有付交感神经系统的抑制,这正是神经节阻断药的严重付作用的原因;也没有*Darenthin是N-O-溴苯甲基-N-乙基-N:N—=甲铵的P-甲苯磺酸临(另名Bretylium tosyl-ate),此外尚有其溴化物,磺化物等。
The authors report in detail about the pharmacological effects of Darenthin and the preliminary results of its clinical trials. Darenthin is a new type of antihypertensive drug that selectively blocks peripheral sympathetic (adrenergic Nervous system) without antagonizing the effects of epinephrine or norepinephrine, and this blockade does not result in inhibition of the sympathetic nervous system, which is exactly why the ganglion blocker exerts a serious effect; nor * Darenthin is NO-bromobenzyl-N-ethyl-N: N- methylammonium p-toluenesulfonate (also known as Bretylium tosyl-ate), in addition to its bromide, sulfonate and the like.