关于动脉粥样硬化(AS)形成的机理有多种学说,但仍不能全面论述其本质。考 虑到胆固醇在短期几十天内就可由正常动脉壁诱导至粥样斑块形成,可能和能量代谢有关,为了维持体内正常运转,势必要多消耗ATP,因此纳、钾-ATP酶活性由于转运K~+,Na~+而相应增高。为此,我们测定了动脉粥样硬化形成时红细胞纳泵活性。 A variety of theories about the mechanism of atherosclerosis (AS) formation, but still can not fully discuss its nature. Taking into account the cholesterol in the short term within a few days can be induced by normal arterial wall to atherosclerotic plaque formation may be related to energy metabolism, in order to maintain the normal operation of the body is bound to consume more ATP, so sodium, potassium-ATPase activity due to transport K ~ +, Na ~ + increased accordingly. To this end, we measured the erythrocyte Na pump activity during atherosclerotic plaque formation.