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家兔失血性休克低血压5．3KPa观察3h，测定平均动脉压（MBP）、左心室收缩压（LVSP）、左心室最大收缩速度（dp／dtmax）以及心肌细胞电生理和组织内外钾钠。结果说明：（1）失血性休克后LVSP下降，且和MBP平行，（2）dp／dtmax在失血性休克后即刻急剧下降，15min后上升48％，以后逐渐下降，3h降至对照值的20％；（3）休克时细胞外钾钠显著升高；（4）心肌细胞静息电位（RP）、动作电位振幅（APH）下降；动作电位复极时间（APD），动作电位复极50％时间（APD50），复极90％时间（APD90）显著延长。提示；心肌细胞快钠通道关闭、慢钠和慢钙通道开放，钠、钙内流，钾外流。
Rabbit hemorrhagic shock hypotension 5.3KPa observed 3h, mean arterial pressure (MBP), left ventricular systolic pressure (LVSP), left ventricular maximum systolic velocity (dp / dtmax) and cardiomyocytes electrophysiological and intra-and extracellular potassium sodium. The results showed that: (1) LVSP decreased after hemorrhagic shock and was parallel with MBP; (2) dp / dtmax decreased sharply immediately after hemorrhagic shock, increased 48% after 15min, then decreased gradually and then decreased to 20 %; (3) extracellular potassium and sodium increased significantly at shock; (4) cardiomyocytes resting potential (RP) and action potential amplitude (APH) decreased; action potential repolarization time Time (APD50), repolarization 90% of the time (APD90) was significantly prolonged. Tip; fast cardiomyocyte sodium channel is closed, slow sodium and slow calcium channels open, sodium, calcium influx, potassium efflux.