约5%的乳腺癌病人初诊即为Ⅳ期乳腺癌~([1]),30%的早期乳腺癌病人在疾病进程中发展为Ⅳ期乳腺癌~([2])。Ⅳ期乳腺癌病人5年相对生存率约24%~([1])。除少数有机会接受局部手术或放疗外,绝大多数病人接受包括化疗、内分泌治疗或靶向治疗在内的系统治疗。传统观点认为,乳房原发灶手术是缓解Ⅳ期乳腺癌病人局部破溃、感染等症状的姑息性治疗,但不能带来生存获益。然而随着筛查技术的进步及系统治疗的发展、低肿瘤负荷Ⅳ期乳腺癌不断出现、Ⅳ期 Approximately 5% of breast cancer patients are newly diagnosed stage IV breast cancer ([1]), and 30% of early breast cancer patients progress to stage IV breast cancer during disease progression. [2] The 5-year relative survival rate of patients with stage IV breast cancer is about 24% ~ ([1]). With the exception of a few who have had the opportunity to undergo local surgery or radiotherapy, the vast majority of patients receive systemic therapy including chemotherapy, endocrine therapy or targeted therapy. The traditional view is that the primary breast surgery is to relieve the palliative treatment of local ulceration and infection of stage IV breast cancer patients, but can not bring about survival benefit. However, with the progress of screening technology and the development of systemic therapy, stage IV breast cancer with low tumor burden continues to emerge. Stage IV