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目的探讨盐酸氨溴索联合布地奈德雾化吸入治疗小儿毛细支气管炎的疗效和安全性。方法将100例小儿毛细支气管炎患儿采用随机数字表法分为两组,均给予祛痰止咳、吸氧、抗炎等对症治疗以及良好护理,治疗组患儿在上述治疗基础上加盐酸氨溴索联合布地奈德雾化吸入治疗,比较观察两组患儿喘憋、咳嗽缓解时间、喘鸣音和啰音消失时间、住院时间以及治愈率。结果治疗组患儿喘憋、咳嗽缓解时间、喘鸣音和啰音消失时间以及住院时间明显少于对照组,治愈率治疗组患儿明显优于对照组,差异均有统计学意义(均P<0.05)。结论盐酸氨溴索联合布地奈德雾化吸入治疗小儿毛细支气管炎有良好的效果,不良反应少。
Objective To investigate the efficacy and safety of ambroxol hydrochloride combined with budesonide inhalation in the treatment of pediatric bronchiolitis. Methods 100 pediatric patients with bronchiolitis were divided into two groups according to the random number table. All patients were given symptomatic treatment of expectorant cough, oxygen inhalation, anti-inflammatory, and good nursing. The treatment group was given ammonia hydrochloride Bromine combined with budesonide inhalation therapy were compared two groups of children with wheezing, cough relief time, wheezing and rales disappear time, hospital stay and cure rate. Results In the treatment group, the patients with asthma, cough relief time, wheeze and rales disappear time and hospital stay were significantly less than the control group, the cure rate in the treatment group was significantly better than the control group, the differences were statistically significant (P <0.05). Conclusion Ambroxol hydrochloride combined with budesonide inhalation treatment of children with bronchiolitis has a good effect, with fewer adverse reactions.