针刺家兔足三里(S36)10min,辐射热测痛法测定痛阈值,针后每5min或7min测定一次,连续观察130min或70min,可见痛阈升高呈周期性波动,其周期为28min,与传统的经气循行周期一致,在此模型上于足三里上下之经线上持续注射微量的酚妥拉明、阿托品或异丙肾上腺素,皆阻断痛阈的升高,而经线注射则无明显影响,表明经络上有兴奋性的α、M受体和抑制性的β受体 Acupuncture rabbits Zusanli (S36) 10min, bolus pain threshold determination of pain threshold, the needle after every 5min or 7min determination, continuous observation of 130min or 70min, we can see the pain threshold increased cyclical fluctuations in the cycle of 28min, Consistent with the traditional menstrual cycle, continuous injection of trace amounts of phentolamine, atropine or isoproterenol into the warp of the upper and lower reaches of Zusanli all blocked the increase of pain threshold, whereas the warp injection There was no significant effect, indicating excitatory alpha, M receptors and inhibitory beta receptors on the meridians