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目的:对他汀类药物治疗冠心病合并高脂血症的临床疗效进行分析。方法:符合相关诊断标准的80例冠心病合并高脂血症患者,保证冠心病常规治疗不变,再联合他汀类药物。专人记录患者的姓名、年龄、基础病、给药的剂量和方式、治疗前后的相关脂蛋白和血脂变化、临床表现、肝肾功能变化、冠心病事件及其它突发情况等。结果:(1)患者治疗后的血脂各指标相比于治疗前显著降低,且均具有统计学意义(P<0.05);(2)就发生率而言,心血管不良事件和病情稳定之间的差异具有显著性(χ~2=14.101,P<0.05)。结论:他汀类药物在用于冠心病合并高脂血症的治疗中不仅较好的调控了血脂,而且极大的改善了愈后。
Objective: To analyze the clinical efficacy of statins in the treatment of coronary heart disease complicated with hyperlipidemia. Methods: According to the diagnostic criteria of 80 cases of coronary heart disease with hyperlipidemia in patients with coronary heart disease to ensure the same treatment, and then combined statins. Patient records the patient’s name, age, basic disease, dosage and mode of administration, changes in lipoprotein and blood lipids before and after treatment, clinical manifestations, liver and kidney function changes, coronary heart disease events and other unexpected situations. Results: (1) The indexes of blood lipids in patients after treatment were significantly lower than those before treatment (both P <0.05); (2) in terms of the incidence, between cardiovascular adverse events and stable disease The difference was significant (χ ~ 2 = 14.101, P <0.05). Conclusion: Statins have not only better regulated blood lipids in the treatment of coronary heart disease complicated with hyperlipidemia, but also greatly improved the prognosis.