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原发性胆汁性肝硬化(PBC)与线粒体抗体(AMA)有密切关联.该病可发展至肝硬化,最后死于肝衰或出血等并发症.晚近报导无症状患者增加,生前不易检测.AMA在有症状及异常肝功[“常规”肝功能试验指血胆红素、碱性磷酸酶(AKP)及氨基转移酶(AST)三项]的PBC病例中已列为诊断指标,但对无症状且肝功能正常者的诊断意义尚未被确认.本研究旨在确定在这类病例中AMA是否确为诊断PBC的标志,并了解这些病例的临床转归.研究对象累计共29例,内有16例自首测AMA阳
Primary biliary cirrhosis (PBC) is closely related to mitochondrial antibody (AMA), which can develop into cirrhosis and finally to complications such as liver failure or bleeding, and asymptomatic patients have recently been reported to be more difficult to detect before birth. AMA has been used as a diagnostic indicator in PBC cases with symptomatic and abnormal liver function [ “routine ” liver function test refers to three items of blood bilirubin, alkaline phosphatase (AKP) and aminotransferase (AST) But the diagnosis of asymptomatic and normal liver function has not yet been confirmed.The purpose of this study was to determine whether AMA in these cases is indeed a marker for the diagnosis of PBC and to understand the clinical outcome of these cases.A total of 29 subjects , There are 16 cases from the first test AMA Yang