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目的观察氨溴索注射液联合干扰素-γ雾化吸入治疗慢性支气管炎急性发作的临床疗效。方法 50例慢性支气管炎急性发作患者(观察组),给予氨溴索注射液联合干扰素-γ雾化吸入进行治疗;并回顾性分析既往收治的单纯采用氨溴索注射液进行治疗的50例(对照组)慢性支气管炎急性发作患者的临床资料,比较两组的临床疗效。结果观察组痊愈24例,显效17例,有效8例,总有效率为98.0%;对照组痊愈13例,显效14例,有效15例,总有效率为84.0%,两组比较差异有统计学意义(P<0.05);观察组临床症状和体征改善时间明显比对照组短(P<0.05),差异有统计学意义。结论氨溴索注射液联合干扰素-γ雾化吸入治疗慢性支气管炎急性发作具有明显疗效,适合临床上广泛应用。
Objective To observe the clinical efficacy of ambroxol injection combined with interferon-γ nebulization in the treatment of acute exacerbation of chronic bronchitis. Methods Fifty patients with acute exacerbation of chronic bronchitis (observation group) were treated with ambroxol injection combined with nebulization of interferon-γ. 50 patients who were treated with ambroxol injection alone were retrospectively analyzed. (Control group) of patients with acute exacerbation of chronic bronchitis clinical data, the clinical efficacy of the two groups were compared. Results The observation group cured 24 cases, markedly effective in 17 cases, effective in 8 cases, the total effective rate was 98.0%; control group cured 13 cases, 14 cases markedly effective in 15 cases, the total effective rate was 84.0%, the difference was statistically significant (P <0.05). The clinical symptoms and signs of the observation group were significantly shorter than those of the control group (P <0.05), and the difference was statistically significant. Conclusion Ambroxol injection combined with interferon-γ nebulization has obvious curative effect on acute exacerbation of chronic bronchitis and is suitable for clinical application.