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到2000年肺癌患者将增加至2百万,其中25%~40%为Ⅲ期。目前已知姑息放疗对缓解症状有益,但在中位生存或长期控制率上无意义。虽然单纯化疗的结果不十分理想,但对经过选择的病例中肿瘤退缩率可达80%。2到4个周期的化疗可使肿瘤缩小,但对放疗耐受量无影响(D_T60Gy~65Gy)。虽然从理论上诱导化疗可能导致肿瘤的放射抗拒性,但还应继续研究。
By the year 2000, the number of lung cancer patients will increase to 2 million, of which 25% to 40% will be phase III. It is currently known that palliative radiotherapy is beneficial for relieving symptoms, but it has no significance in median survival or long-term control. Although the results of chemotherapy alone are not ideal, the rate of tumor regression in selected cases can reach 80%. Two to four cycles of chemotherapy resulted in tumor shrinkage but no effect on radiotherapy tolerance (D_T60Gy~65Gy). Although theoretical induction of chemotherapy may lead to radiation resistance of tumors, it should continue to be studied.