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用双盲、随机、无效对照研究840例60岁以上高血压患者的抗高血压治疗,其主要结果已报告(Amery,1985),表明心血管病治疗组死亡率显著低于安慰剂组。本文分析其抗高血压治疗的副作用。方法:坐位血压为21.3～31.8/12.0～15.8 kpa 的60岁以上患者随机分为氨苯喋啶+氢氯噻嗪组416例,安慰剂组424例,当血压持续高水平时均加用甲基多巴。进入研究后相关疾病和症状每年记录一次,高血压以国际标准疾病分类第8次修订标准为诊断
A double-blind, randomized, placebo-controlled study of antihypertensive treatment in 840 patients over 60 years of age with hypertension has reported primary results (Amery, 1985), indicating that mortality was significantly lower in the cardiovascular-disease arm than in the placebo arm. This article analyzes the side effects of antihypertensive treatment. Methods: A total of 416 patients aged 60 years or older with seating pressure of 21.3 ~ 31.8 / 12.0 ~ 15.8 kPa were randomly assigned to methotrexate + hydrochlorothiazide group and 424 patients in placebo group. When blood pressure was high, methyldopa . After entering the study related diseases and symptoms recorded once a year, high blood pressure in accordance with the International Standard Classification of Diseases, the 8th revision criteria for the diagnosis