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狂犬病是由狂犬病病毒引起的高度致死性的人兽共患传染病,口服粘膜免疫方式是控制狂犬病极为有效的防控措施。粘膜免疫系统构成了机体抵抗病原体入侵的第一道免疫屏障,新型动物用狂犬病口服疫苗研制已形成了一个新的前沿和焦点,具有很好的研究前景和优势。
Rabies is a highly lethal zoonosis caused by rabies virus. Oral mucosal immunization is a very effective prevention and control measure to control rabies. The mucosal immune system constitutes the first immune barrier against the invasion of pathogens. The development of oral rabies vaccine for new animals has formed a new frontier and focus, which has good research prospects and advantages.