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目的:观察不同剂量间苯三酚治疗分娩过程中宫颈水肿的疗效。方法:选择正常初产妇、宫口开大2~3cm后出现宫颈水肿160例,随机分为3个组:A组(55例):间苯三酚40mg宫颈封闭+80mg静推(15min后);B组(55例):间苯三酚80mg静推;C组(50例):654-210mg静推。结果:A组2h宫口扩张(2.8±0.7)cm,至宫口开全需(2.6±0.2)h,扩张速度及时间明显优于B、C组(P<0.01),三组在第二产程时间、2h宫颈水肿消失情况、分娩方式及新生儿窒息情况上比较,差异无统计学意义(P>0.05)。结论:间苯三酚40mg宫颈封闭+80mg静推,充分利用了药物的特性,在促进产程进展上疗效显著,值得临床进一步研究推广。
Objective: To observe the efficacy of different doses of phloroglucinol in the treatment of cervical edema during labor. Methods: 160 cases of cervical edema were randomly divided into three groups: Group A (55 cases): 40 mg of cystine and 80 mg of static phlebotomy (after 15 minutes) ; Group B (55 cases): phloroglucinol 80mg static push; C group (50 cases): 654-210mg static push. Results: In group A, the cervix was expanded at 2.8 ± 0.7 cm and the required rate was 2.6 ± 0.2 h at cervix. The speed and duration of expansion were significantly better than those in group B and C (P <0.01) Labor time, disappearance of cervical edema 2h, mode of delivery and neonatal asphyxia, the difference was not statistically significant (P> 0.05). Conclusion: 40mg of phloroglucinol is effective in the process of labor process, which is worthy of clinical further study and promotion.