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鉴于现代高电压放射治疗的应用,盆腔淋巴结易于得到足够的放射肿瘤治疗量。因此,作者对Ⅰ期宫内膜癌进行术后外照射治疗的前瞻性研究,以期确定该治疗是否可提高患者的治疗效果。挪威镭锭医院于1968～1974年,共收治Ⅰ期宫内膜癌540例。在手术(全子宫及双侧附件切除)及阴道镭疗(剂量6,000rads)后,随机分为两组。A组(277例)不再作进一步治疗;B组(263例)接受高电压外照射,剂量为4,000rads肿瘤量。两组患者的年龄、体重、宫腔深度、宫壁浸润深度及组织学分级等的分布情况均极相似。结果可见A组及B组的五年存活率分别为91%及89%;九年存活率为90%及87%,无明显差异。
In view of the application of modern high-voltage radiotherapy, pelvic lymph nodes tend to get enough radiation treatment of tumors. Therefore, the authors of phase I endometrial cancer postoperative external beam radiotherapy for the prospective study to determine whether the treatment can improve the therapeutic effect of patients. Norwegian radium ingot hospital from 1968 to 1974, a total of 540 cases of endometrial cancer were treated. After surgery (total hysterectomy and bilateral attachment excision) and vaginal laser therapy (6,000rads), they were randomly divided into two groups. Group A (277 cases) was not treated further; Group B (263 cases) received high voltage external irradiation at a dose of 4,000 rads of tumor volume. The distribution of age, weight, uterine cavity depth, depth of uterine wall invasion and histological grading of the two groups were very similar. The results showed that the five-year survival rates of group A and group B were 91% and 89%, respectively. The nine-year survival rates were 90% and 87%, respectively. There was no significant difference.