论文部分内容阅读
类似乳腺分泌性癌(mammary analogue secretory carcinoma,MASC)的涎腺肿瘤2010年由Skalova首次描述,其组织病理学及免疫组化(mamaglobin和S-100染色双阳性)均类似于乳腺分泌性癌,且存在特征性ETV6基因易位的涎腺肿瘤。mamaglobin和S-100染色有助于MASC的涎腺肿瘤的鉴别诊断,尤其是与形态学酷似MASC的腺泡细胞癌和非特异性腺癌的鉴别。但联合应用这两种抗体在其它具有灶性
Salivary gland tumors like mammary analogue secretory carcinoma (MASC) were first described by Skalova in 2010 and their histopathology and immunohistochemistry (both positive for mamaglobin and S-100 stain) are similar to those for breast-secreting carcinoma, There are salivary gland tumors characterized by the translocation of the ETV6 gene. Mamaglobin and S-100 staining contribute to the differential diagnosis of salivary gland tumors in MASC, especially the identification of acinar cell carcinoma and nonspecific adenocarcinoma with morphology resembling MASC. However, the combination of these two antibodies is focal in others