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英国安全用药委员会收到了365篇报告,内容是与血管紧张素转化酶抑制剂有关的咳嗽,这些药物越来越多的用于治疗高血压和心力衰竭.咳嗽的特点是持续性干咳,躺下时加重,引起喉部刺激性感觉. 据报告,咳嗽至少是四种血管紧张素转化酶抑制剂的副作用,所有这类药物都可引起咳嗽,但很难认识到咳嗽是一种副作用,因为咳嗽属常见,传统上不将其与药物相联系.另外,开始治疗后几周甚至几个月,咳嗽可能不明显.因此,已发表的研究报告对咳嗽未进行前瞻性探索.在至少有250名病人参加的研究中,与血管紧张素转化酶抑制剂有关的咳嗽发生率为0-3％,但在高血压诊所就诊的两小组病人的研究表
The SEC reported 365 reports of cough associated with ACE inhibitors, which are increasingly used to treat high blood pressure and heart failure. Cough is characterized by persistent dry cough, lying down When it aggravates the throat irritation.5 Coughing has been reported as a side effect of at least four angiotensin-converting enzyme inhibitors, all of which can cause coughing, but it is difficult to recognize that coughing is a side-effect because coughing Are not traditionally associated with drugs, and cough may not be apparent in the weeks or even months after the start of the treatment, so published studies have not prospectively explored cough, with at least 250 In patients enrolled, the incidence of cough associated with ACE inhibitors was 0-3%, but the study of two groups of patients treated at the hypertensive clinic