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目的:观察脑钠尿肽(BNP)以及超敏C反应蛋白(hs-CRP)联合检测在诊断急性冠脉综合征(ACS)中的临床意义。方法:选择2012年1月至2012年12月我院收治的96例ACS患者作为研究组,同期我院收治的94例稳定型心绞痛(SAP)患者作为SAP组,另外选择2012年1月至2012年12月90例来我院进行健康体检者作为对照组,检测三组血清hs-CRP和BNP的水平。结果:研究组和SAP组血清hs-CRP和BNP的水平均明显高于对照组,且研究组血清hs-CRP和BNP的水平高于SAP组,差异均有统计学意义(P<0.05)。结论:联合检测血清BNP与hs-CRP水平对于诊断ACS有着十分重要的临床价值,考虑用于ACS诊断。
Objective: To observe the clinical significance of combined detection of brain natriuretic peptide (BNP) and high-sensitivity C-reactive protein (hs-CRP) in the diagnosis of acute coronary syndrome (ACS). Methods: A total of 96 patients with ACS admitted to our hospital from January 2012 to December 2012 were enrolled in the study. 94 patients with stable angina pectoris (SAP) admitted to our hospital during the same period were enrolled as SAP group. In addition, January 2012 to 2012 December 90 cases to our hospital for physical examination as a control group, serum hs-CRP and BNP levels were detected. Results: The serum levels of hs-CRP and BNP in study group and SAP group were significantly higher than those in control group. The levels of serum hs-CRP and BNP in study group and SAP group were significantly higher than those in SAP group (P <0.05). Conclusions: The combined detection of serum BNP and hs-CRP levels is of great clinical value in the diagnosis of ACS and is considered for ACS diagnosis.