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组织胞浆菌病是世界上广泛流行的一种原发性呼吸系统真菌病。主要流行于美国密西西比河和俄亥俄河流域;中美洲、南美洲、印度、塞浦路斯、东南亚等地区也有报道;欧洲和澳大利亚罕见。至今国内个案报道共6例。Whcat等估计每年有50多万人感染本菌;90~95%呈无症状型;慢性肺型和播散型发生率分别为5/1万和2/10万。病因和发病机理:病原体为荚膜组织胞浆菌,属双相性真菌,在37℃和感染的宿主体内呈酵母型,
Histoplasmosis is a type of primary respiratory fungal disease that is prevalent in the world. Mainly popular in the United States Mississippi and Ohio River basin; Central America, South America, India, Cyprus, Southeast Asia and other regions have also been reported; Europe and Australia rare. So far a total of 6 cases reported in China. Whcat et al estimated that more than 500,000 people were infected with this bacterium annually; 90 to 95% were asymptomatic; and chronic lung and disseminated rates were 5/1 and 2/10 respectively. Etiology and pathogenesis: The pathogen is Histoplasma capsulatum, is a biphasic fungi, at 37 ℃ and infected host was yeast type,