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目的：观察息宁（左旋多巴／ 卡比多巴）对难治性屈光参差性弱视患儿视力的影响，探讨左旋多巴用药时间和治疗机理。方法：给３２ 例（５～１５ 岁） 经传统疗法治疗至少６ 个月无效的屈光参差性弱视患儿口服息宁１ｍｇ／０．２５ｍｇ／ｋｇ，一日三次，连续６０ 天。观察服药前及服药后第３、６、９ 、３０、６０ 天单字Ｅ 视力的变化。结果：弱视眼和优势眼的单字视力服药后第３ 天提高，差异有极显著性（ Ｐ＜０ ．０１） ，继续服药无进一步改善。结论：短期服用左旋多巴对改善难治性屈光参差性弱视的视力有一定作用。
Objective: To observe the effect of Xining (levodopa / carbidopa) on visual acuity in children with refractory anisometropic amblyopia and to explore the levodopa treatment time and therapeutic mechanism. Methods: 32 patients (5-15 years old) who were treated with traditional therapy for atypical anisometropic amblyopia for at least 6 months were treated with oral Xining 1mg / 0.25mg / kg three times a day for 60 consecutive days. Observation of medication before and after taking the 3rd, 6th, 9th, 30th and 60th days of single word E vision changes. Results: The visual acuity of amblyopic eye and dominant eye increased 3 days after taking the medicine, the difference was significant (P <0.01). No further improvement was continued after taking the medicine. Conclusion: Short-term administration of levodopa has some effect on improving visual acuity in refractory and anisometropic amblyopia.