抗凋亡因子Survivin是近年来发现的凋亡抑制蛋白,Ki-67是一种与细胞周期相关的增殖细胞核抗原,它们都具有抗凋亡、促进肿瘤细胞增殖的作用。研究发现Survivin、Ki-67与妇科肿瘤的发生、发展及预后密切相关,而且可以作为一个新的靶点对肿瘤进行基因治疗。本文就Survivin、Ki-67 Anti-apoptotic factor Survivin is an apoptosis-inhibiting protein found in recent years. Ki-67 is a proliferating cell nuclear antigen associated with the cell cycle. Both of them have anti-apoptotic effects and promote the proliferation of tumor cells. The study found that Survivin, Ki-67 and gynecological tumors are closely related to the occurrence, development and prognosis, and can be used as a new target for tumor gene therapy. This article on Survivin, Ki-67