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对大白鼠组织作DNA拓扑弄构酶Ⅰ(拓扑酶Ⅰ)活力测定,见酶活力出现在胚胎早期,在胚胎发育过程及出生后不同年龄期,酶活力基本稳定;几种成年大鼠组织的酶活力彼此无显著差异;肝细胞再生及癌变,酶活力亦无显著变化。
For the determination of DNA topology isoenzyme I (topological enzyme I) activity in rat tissues, the enzyme activity appears in the early stage of the embryo. During the embryonic development and at different ages after birth, the enzyme activity is basically stable; several adult rat tissues There was no significant difference in enzyme activity between the two groups; there was no significant change in hepatocyte regeneration and canceration and enzyme activity.