兔耳静脉或肝门静脉注入凝血酶,可造成实验性弥漫性血管内凝血。电镜见枯否氏细胞对纤维素的反应有三个阶段:1.枯否氏细胞表面吸附纤维素;2.枯否氏细胞膜内陷反折,逐渐形成复杂的蠕虫样和迷宫样结构。由于胞膜反折,枯否氏细胞吸附纤维素的面积增加。蠕虫样和迷宫样结构内包裹大量纤维素; Rabbit ear vein or hepatic portal vein injection of thrombin, can cause experimental diffuse intravascular coagulation. Electron microscopy see Kupffer cells reaction to cellulose has three stages: 1. Kupffer cell surface adsorption of cellulose; 2. Kushan cell membrane invagination refolding, and gradually form a complex worm-like and maze-like structure. Due to membrane refolding, Kupffer cells adsorbed cellulose increased in area. Worm-like and maze-like structures enclose a large amount of cellulose;