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目的:探讨龈下刮治配合补肾固齿丸对中、重度牙周炎的短期治疗效果。方法:纳入中、重度牙周炎患者共44例,随机分为两组,每位患者选择2颗指数牙。所有患者试验前均进行龈上洁治和龈下刮治,试验组同时给予口服补肾固齿丸4 g/次,2次/日,连服3个月。测定治疗前后指数牙的探诊出血(BOP)、探诊深度(PD)、附着丧失(AL)及其牙槽骨平均灰度值(MGVs)。结果:试验组BOP阳性率、PD和AL均较治疗前有明显下降(P<0.05),而MGVs升高(P<0.05)。对照组治疗后BOP阳性率和PD明显降低(P<0.05),但AL及MGVs无明显改善(P>0.05)。试验组与对照组对中、重度牙周炎的短期疗效有显著差异(P<0.05)。结论:龈下刮治配合口服补肾固齿丸治疗中、重度牙周炎的短期疗效明显优于单纯龈下刮治组,可能与补肾固齿丸能促进牙槽骨新骨形成、降低AL有关。
Objective: To investigate the short-term therapeutic effect of subgingival scaling combined with Bushen Guotai Wan on moderate and severe periodontitis. Methods: A total of 44 patients with moderate and severe periodontitis were enrolled and randomly divided into two groups. Two index teeth were selected for each patient. All patients were treated with supragingivalgia and subgingival scaling before the test. The patients in the experimental group were given oral Bu Shen Gu Pill 4 g once daily for 3 months. The BOP, PD, AL, and mean alveolar bone tone (MGVs) of exponential tooth before and after treatment were measured. Results: The positive rate of BOP in experimental group was significantly lower than that before treatment (P <0.05), while the level of MGVs was higher in experimental group (P <0.05). The positive rate of BOP and PD in the control group were significantly decreased (P <0.05), but no significant improvement was found in AL and MGVs (P> 0.05). The short-term curative effect of the experimental group and the control group on moderate and severe periodontitis was significantly different (P <0.05). Conclusion: The subgingival cure combined with oral administration of Bushen Guotou Pill has obvious short-term curative effect on moderate and severe periodontitis compared with simple subgingival curettage group, which may be related to the effect of Bushen Guotai Pill on alveolar bone formation and AL reduction .