疣状胃炎(gastritis errucosa简称VG),是一种常见的并有特征形态和病理变化的胃炎,又称慢性糜烂性胃炎、痘疹样糜烂等,因其可恶变,甚为人们所关注。VG的病因至今不清楚,有人认为与过敏、免疫抑制、抗生素等因素有关。近年研究认为,幽门螺杆菌(Hp)感染与VG的形成有关。本研究旨在探讨Hp感染尤其是产生细胞毒素相关蛋白A(CagA)的Hp感染与VG发生发展的关系。一、材料和方法 (一) 材料胃粘膜组织标本:全部来自西安市中心医院消化科门诊患者,经胃镜检查及病理组织学 Gastritis (gastritis errucosa referred to as VG), is a common and characterized by morphological and pathological changes of gastritis, also known as chronic erosive gastritis, pox-like erosion and so on, because of its malignant transformation, very much attention. The etiology of VG is still unclear, some people think and allergies, immunosuppression, antibiotics and other factors. Recent studies suggest that Helicobacter pylori (Hp) infection and the formation of VG. This study aimed to investigate the relationship between Hp infection and Hp infection, especially CagA-producing Hp infection. First, the material and methods (A) material Gastric mucosa specimens: all from the Central Hospital of Xi’an Gastroenterology outpatient, by gastroscopy and histopathology