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本文报告了48例急性脑血栓形成患者用川芎嗪治疗前后六项血液流变性指标的测定结果,以25例年龄、性别与病人组构成相近的正常人作对照组。病人组治疗前此六项指标与对照组相比均有显著差异(P<0.01),此异常改变在本病的发生上可能起着重要作用。治疗后。此六项指标明显改善,且与临床症状的好转呈平行关系。提高红细胞和血小板表面电荷、减少它们的聚集、改善血液流变性和微循环可能是该药治疗本病取得疗效的主要原因之一。
In this paper, 48 patients with acute cerebral thrombosis before and after treatment with ligustrazine measured the results of the six hemorrheological indicators, 25 cases of age, gender and the patient group similar to the normal control group. Before treatment, the six indexes in the patient group were significantly different from those in the control group (P <0.01). This abnormal change may play an important role in the occurrence of this disease. After treatment. The six indicators improved significantly, and with the improvement of clinical symptoms showed a parallel relationship. Increasing the surface charges of red blood cells and platelets, reducing their aggregation, improving blood rheology and microcirculation may be one of the main reasons for the efficacy of the drug in the treatment of this disease.