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应用渗析液间接测定了大鼠出血性休克不同时相时血液和肝组织中萄萄糖和乳酸浓度，观察了其时相性变化和相关性，并用电子显微镜观察了肝细胞的形态学变化．结果表明，休克初期２种物质浓度在血液和肝脏中均急剧上升，休克９０ｍｉｎ时血液和肝组织中萄萄糖浓度分别达到最高值（２２．１±３．４）ｍｍｏｌ／Ｌ和（１６．５±２．０）ｍｍｏｌ／Ｌ，后逐渐下降．肝组织中乳酸浓度在休克９０ｍｉｎ时达最高值（１１．６±２．６）ｍｍｏｌ／Ｌ，后下降，而血中乳酸值在休克１２０ｍｉｎ时达最高值（１６．５±２．７）ｍｍｏｌ／Ｌ，后虽缓慢下降，但动物仍处于高乳酸血症状态．休克９０ｍｉｎ后肝细胞超微结构已开始受损，糖原颗粒减少．
The concentrations of glucose and lactate in blood and liver tissue were measured indirectly with dialysate at different time phases of hemorrhagic shock in rats. The changes of the phase and the correlation between them were observed. The morphological changes of hepatocytes were observed under electron microscope. The results showed that the concentrations of both substances in blood and liver increased sharply in the early stage of shock, and reached the highest values (22.1 ± 3.4) mmol / L and (16.1 ± 3.4) mmol / L in blood and liver tissue at 90 min after shock, respectively. 5 ± 2.0) mmol / L, then decreased gradually. Lactate concentration in liver tissue reached the highest value (11.6 ± 2.6) mmol / L at 90 min after shock and then decreased, while the lactate level in blood reached the highest value (16.5 ± 2.7) mmol at 120 min after shock / L, after a slow decline, but the animals are still in the state of hyperlipidemia. After 90 minutes of shock, the ultrastructure of hepatocytes has begun to be impaired, reducing glycogen granules.