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内皮素（ＥＴ）在其生物合成过程中，由其较大的前体分子──ｂｉｇＥＴ经内皮素转换酶（ＥＣＥ）作用水解去掉部分氨基酸而来。ＥＣＥ在调节ＥＴ生物学活性方面起着十分重要的作用。
Endothelin (ET) in its biosynthesis process, from its larger precursor molecule ─ ─ bigET by endothelin-converting enzyme (ECE) hydrolysis by removing part of the amino acids from. ECE plays a very important role in regulating ET biological activity.