非整倍体常与人类恶性肿瘤及癌前病变相关连。在结肠、骨、肺、乳腺、膀胱、前列腺和卵巢的恶性肿瘤中均已证实:DNA含量与预后呈反比。作者于1980～1984年运用流体细胞计数研究了不同分级的原位癌53例和浸润癌33例的宫颈活检标本。恶性上皮细胞出现比例为3～90％,平均为56％。 Aneuploidy is often associated with human malignancies and precancerous lesions. It has been demonstrated in cancers of the colon, bone, lung, breast, bladder, prostate and ovary that the DNA content is inversely proportional to the prognosis. From 1980 to 1984, the authors used fluid cytometry to study cervical biopsy specimens of 53 different-grade carcinoma in situ and 33 invasive carcinoma. Malignant epithelial cells appeared in 3 ~ 90%, with an average of 56%.