论文部分内容阅读
目的探讨中国成人多重心血管危险因素聚集的最佳腰围切割点。方法分析1994年全国糖尿病普查的15628例年龄≥25岁的中国成人资料。以腰围<70cm组(每隔5cm分为一组)作为对照,计算其他各组发生多重心血管危险因素的优势比OR值和95%CI。采用ROC曲线分析计算不同腰围水平对多重心血管危险因素聚集识别的敏感性和特异性,以诊断指数(诊断指数=1-假阳性-假阴性)最大的腰围作为最佳切割点。结果无论男性还是女性,胰岛素抵抗、血脂异常、高血压和高血糖的百分比均随着腰围的增加而增加。男性腰围≥85cm、女性腰围≥80cm后发生代谢综合征的OR值显著增加[分别为2.08(95%CI1.80～2.39)和1.66(95%CI1.41～1.97)]。ROC分析显示以上相应腰围切割点具有最佳的敏感性和特异性。结论反映中国成人多重心血管危险因素聚集的男性最佳腰围切割点为85cm、女性为80cm。
Objective To investigate the best waist-cut point for aggregation of multiple cardiovascular risk factors in Chinese adults. Methods The data of 15 568 Chinese adults aged> 25 years old from the 1994 National Diabetes Census were analyzed. The odds ratio (OR) and 95% CI (CI) of odds ratios for multiple cardiovascular risk factors in each of the other groups were calculated using the waist circumference <70 cm group divided into groups of 5 cm. ROC curve analysis was used to calculate the sensitivity and specificity of different waistline levels for the identification of multiple cardiovascular risk factors. The best waist circumference with the highest diagnostic index (diagnostic index = 1 - false positive - false negative) was selected as the best cut point. Results Both men and women, the percentage of insulin resistance, dyslipidemia, hypertension and hyperglycemia increased with increasing waist circumference. The odds ratio for metabolic syndrome was significantly increased in men with a waist circumference ≥85 cm and waist circumference ≥80 cm [2.08 (95% CI 1.80-2.39) and 1.66 (95% CI 1.41-1.97, respectively)]. The ROC analysis showed the best sensitivity and specificity for the above cut points. Conclusions The best waist circumference cut-off point for male adults with multiple cardiovascular risk factors in China is 85 cm and female is 80 cm.