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目的探讨宫颈环形电切术(LEEP)治疗宫颈上皮内瘤变(CIN)的临床意义和适宜人群。方法回顾分析2007年1月至2009年6月接受LEEP术的352例患者(CIN 330例,原位癌22例),对患者一般情况、术前阴道镜定位活检、术中情况、术后病理结果和随访资料进行统计分析。结果①术前、术后、宫颈环切组织病理结果比较,病理分级一致者210例(59.5%),级别下降者100例(28.4%),余42例(12.2%)级别上升,其中3例术前为CIN I而术后证实为CINⅢ(不包括原位癌),②对所有患者定期随访至2010年12月CIN治愈307例(93%),病变残留23例(6.9%),CINI中1例(0.33%)术后6个月复发。结论 LEEP术治疗CIN治愈率高,复发率低,病变残留复发率低,是正确可行的治疗方法。
Objective To investigate the clinical significance and appropriate population of cervical ring excision (LEEP) in the treatment of cervical intraepithelial neoplasia (CIN). Methods A total of 352 patients (330 CIN and 22 carcinoma in situ) undergoing LEEP from January 2007 to June 2009 were retrospectively analyzed. The general condition, preoperative colposcopy biopsy, intraoperative status, postoperative pathology Results and follow-up data for statistical analysis. Results ① The pathological results of the cervical circumcision were 210 cases (59.5%), 100 cases (28.4%), and the remaining 42 cases (12.2%) were increased before operation, Preoperatively CIN I was confirmed as CIN III postoperatively (excluding carcinoma in situ); ② All patients were regularly followed up until December 2010 with a CINI of 307 (93%) and 23 lesions (6.9%) with CINI One patient (0.33%) relapsed 6 months after operation. Conclusion LEEP treatment of CIN high cure rate, low recurrence rate, residual disease recurrence rate is low, is the correct and feasible treatment.