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病例:女,65岁。1991年9月19日入院,确诊为风湿性心脏病伴二尖瓣狭窄与关闭不全,慢性充血性心力衰竭,心功能Ⅳ级,心房纤颤。在常规应用地高辛、速尿、潘生丁的基础上,加服巯甲丙脯酸12.5毫克,3次/日。用药7天后,干咳呈阵发性进行性加重,活动后及夜间更甚。考虑为心力衰竭加重所致,便将巯甲丙脯酸剂量加倍,3天后咳嗽更甚,呈持续性刺激性干咳,服药后15分钟至2小时及夜间重。体检:体温正常,颈静脉已无充盈,双肺底湿性啰音消失,心率86次/分,房颤心律,心脏杂音无改变。原肿大的肝脏趋于正常,双下肢浮肿基本消退。
Case: female, 65 years old. September 19, 1991 admitted to hospital, diagnosed with rheumatic heart disease with mitral stenosis and insufficiency, chronic congestive heart failure, cardiac function Ⅳ, atrial fibrillation. In the conventional application of digoxin, furosemide, dipyridamole, based on the addition of captopril 12.5 mg, 3 times / day. After 7 days of medication, dry cough was paroxysmal progressive aggravated, activity and night even more. Considered to be due to increased heart failure, will double the dose of captopril, cough even more after 3 days, was persistent irritating dry cough, taking 15 minutes to 2 hours and night weight. Physical examination: normal body temperature, no filling of the jugular vein, end of double lung wet rales disappear, heart rate 86 beats / min, atrial fibrillation, heart murmur no change. The original enlargement of the liver tends to be normal, edema of both lower extremities subsided.