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1972年Murphy等提出慢性精神分裂症患者血小板单胺氧化酶(MAO)活力低下,但精神病临床研究者报告的结果不—。我们对本市精神病疗养院非药物治疗的住院患者50例(男28例,女22例;年龄28～71岁,病程8～41年,平均21.66年;停服抗精神病药物时间半年～16年),进行MAO活力测定。测定前尿吩噻嗪试验均为阴性。另对正常健康人50例(男28例,女22例;年龄34～82岁,身体健康。无精神病家族史)作对照,以观察其对精神分裂症的诊断价值。
In 1972, Murphy et al. Proposed that patients with chronic schizophrenia have low activity of platelet monoamine oxidase (MAO), but the results reported by clinical psychiatrists are not-. In our psychiatric nursing home in our hospital, 50 cases of non-drug-treated inpatients (28 males and 22 females; aged 28 to 71 years, duration of 8 to 41 years, an average of 21.66 years; antipsychotics stopped for six months to 16 years) MAO activity determination. Before the test urinary thiazide test were negative. Another 50 cases of normal healthy people (28 males and 22 females; aged 34 to 82 years, healthy and without psychiatric family history) as a control, to observe its diagnostic value of schizophrenia.