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目的对比奥曲肽、垂体后叶素治疗肝硬化上消化道出血的疗效。方法选取2015年10月至2016年10月入院接受治疗的肝硬化上消化道出血患者74例,将患者按照随机数字法分为观察组和对照组,每组各37例,观察组和对照组分别采用奥曲肽和垂体后叶素进行治疗,对比2组治疗后的效果。结果观察组的治疗总有效率为91.18%,明显优于对照组的61.76%,观察组不良反应发生率明显低于对照组。结论采用奥曲肽对肝硬化上消化道出血进行治疗,安全性较高,效果显著,未出现不良反应,疗效优于垂体后叶素治疗效果。
Objective To compare the efficacy of octreotide and vasopressin in the treatment of upper gastrointestinal bleeding in cirrhosis. Methods Totally 74 patients with cirrhosis and upper gastrointestinal bleeding were admitted to our hospital from October 2015 to October 2016. The patients were divided into observation group and control group according to random number method, 37 cases in each group, observation group and control group The patients were treated with octreotide and vasopressin respectively, and the results were compared between the two groups. Results The total effective rate of the observation group was 91.18%, which was significantly better than that of the control group (61.76%). The incidence of adverse reactions in the observation group was significantly lower than that of the control group. Conclusions The use of octreotide in the treatment of cirrhosis and upper gastrointestinal bleeding is safe and effective with no adverse reactions. The curative effect is superior to that of pituitrin.