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目的探索利用超微型光纤成像系统获得离体猪肺细支气管(直径<1mm)图像的可行性。方法将超微型光纤成像系统的光纤(直径0.82mm)自10具完整新鲜猪肺标本的喉部插入,连接CPAP(Continuous Positive Airway Pressure)模式无创呼吸机,观察并记录各级细支气管解剖结构、黏膜颜色、气管内分泌物等;插入到支气管远端遇到阻力时停止,固定光纤后行肺CT扫描,并行支气管三维重建,获取超微型光纤到达最远端支气管的直径。结果超微型光纤成像系统能实时获得各级细支气管图像;三维重建图像显示超微型光纤成像系统能到达直径<1mm的细支气管。结论利用超微型光纤成像系统能获得离体猪肺直径<1mm的细支气管的图像,可为获得活体肺细支气管图像提供前期动物研究基础。
Objective To explore the feasibility of obtaining images of bronchiobronchial bronchus (diameter <1 mm) in vitro using an ultrafine fiber optic imaging system. Methods The optical fiber (diameter 0.82mm) of the ultrafine fiber imaging system was inserted from the larynx of 10 intact fresh pig lung specimens. CPAP (Continuous Positive Airway Pressure) noninvasive ventilator was used to observe and record the bronchial anatomy at all levels, Mucosa color, endotracheal tube, etc .; inserted into the distal end of the bronchus to stop when resistance is encountered, after fixation of the fiber lung CT scan, three-dimensional reconstruction of bronchial parallel to obtain the diameter of the most distal bronchus to reach the micro-fiber. Results The micro-fiber imaging system can obtain the bronchioles at all levels in real time. The 3D reconstruction images show that the micro-fiber imaging system can reach the bronchioles <1mm in diameter. Conclusion The image of bronchiole with <1mm in vitro pig lung diameter can be obtained by using the ultrafine fiber imaging system, which can provide the basis for early animal research in obtaining the bronchiole bronchus in vivo.