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某些心血管病发生和发展的机理与免疫应答异常、免疫调节差异或免疫遗传有关。病原体感染或感染后,机体可出现交叉免疫或自身免疫病理变化,损害心血管组织,如风湿性心脏炎、感染性心内膜炎及病毒性心肌炎等。自身免疫病中,T 细胞亚群和 NK 细胞数量或/和功能异常,免疫调节差异和免疫监视失控,常常使心血管组织成为异常细胞和体液免疫反应的靶标。心脏损伤、动脉粥样硬化、高血压病等均可能涉及免疫学问题。然而,多数心血管病的免疫学研究尚待进一步深化。
Some of the cardiovascular pathogenesis and development of the mechanism and abnormal immune response, immunomodulation differences or immune genetic. Pathogen infection or infection, the body may appear cross-immune or autoimmune pathological changes, damage to cardiovascular tissue, such as rheumatic carditis, infective endocarditis and viral myocarditis. In autoimmune diseases, the number and / or dysfunction of T-cell subsets and NK cells, differences in immunoregulatory and uncontrolled immune surveillance often make cardiovascular tissue a target of abnormal cellular and humoral immune responses. Cardiac damage, atherosclerosis, hypertension and so on may involve immunological problems. However, the immunological study of most cardiovascular diseases remains to be further deepened.